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1

CRISPR germline engineering—the community speaks

Bosley, Katrine S, Botchan, Michael, Bredenoord, Annelien L, Carroll, Dana, Charo, R Alta, Charpentier, Emmanuelle, Cohen, Ron, Corn, Jacob, Doudna, Jennifer, Feng, Guoping, Greely, Henry T, Isasi, Ro

Journal:

Nature Biotechnology

Year:

2015

Language:

english

File:

PDF, 3.28 MB

english, 2015

2

From Privacy to Data Protection in the EU: Implications for Big Data Health Research

Mostert, Menno, Bredenoord, Annelien L., van der Slootb, Bart, van Delden, Johannes J.M.

Journal:

European Journal of Health Law

Year:

2017

Language:

english

File:

PDF, 506 KB

english, 2017

3

Human tissues in a dish: The research and ethical implications of organoid technology

Bredenoord, Annelien L., Clevers, Hans, Knoblich, Juergen A.

Journal:

Year:

2017

Language:

english

File:

PDF, 1022 KB

english, 2017

4

Toward a “Post-Posthuman Dignity Area” in Evaluating Emerging Enhancement Technologies

Bredenoord, Annelien L., Graaf, Rieke van der, van Delden, Johannes J. M.

Journal:

American Journal of Bioethics

Year:

2010

Language:

english

File:

PDF, 74 KB

english, 2010

5

The FAIR guiding principles for data stewardship: fair enough?

Boeckhout, Martin, Zielhuis, Gerhard A., Bredenoord, Annelien L.

Journal:

European Journal of Human Genetics

Year:

2018

Language:

english

File:

PDF, 395 KB

english, 2018

6

Passive data collection and use in healthcare: a systematic review of ethical issues

Maher, Nicole A., Senders, Joeky T., Hulsbergen, Alexander F.C., Lamba, Nayan, Parker, Michael, Onnela, Jukka-Pekka, Bredenoord, Annelien L, Smith, Timothy R, Broekman, Marike LD

Journal:

International Journal of Medical Informatics

Year:

2019

Language:

english

File:

PDF, 599 KB

english, 2019

7

Ethical implications of regenerative medicine in orthopedics: an empirical study with surgeons and scientists in the field

Niemansburg, Sophie L., van Delden, Johannes J.M., Öner, F. Cumhur, Dhert, Wouter J.A., Bredenoord, Annelien L.

Journal:

The Spine Journal

Year:

2014

Language:

english

File:

PDF, 214 KB

english, 2014

8

Scientific Evaluation of Spinal Implants

Moojen, Wouter A., Bredenoord, Annelien L., Viergever, Roderik F., Peul, Wilco C.

Journal:

Year:

2014

Language:

english

File:

PDF, 113 KB

english, 2014

9

Big Data in medical research and EU data protection law: challenges to the consent or anonymise approach

Mostert, Menno, Bredenoord, Annelien L, Biesaart, Monique C I H, van Delden, Johannes J M

Journal:

European Journal of Human Genetics

Year:

2015

Language:

english

File:

PDF, 255 KB

english, 2015

10

Should the 14‐day rule for embryo research become the 28‐day rule?

Appleby, John B, Bredenoord, Annelien L

Journal:

EMBO Molecular Medicine

Year:

2018

Language:

english

File:

PDF, 205 KB

english, 2018

11

Feedback of individual genetic results to research participants: in favor of a qualified disclosure policy

Annelien L. Bredenoord, N. Charlotte Onland-Moret, Johannes J.M. Van Delden

Journal:

Year:

2011

Language:

english

File:

PDF, 141 KB

english, 2011

12

Preimplantation genetic diagnosis for mitochondrial DNA disorders: ethical guidance for clinical practice

Bredenoord, Annelien, Dondorp, Wybo, Pennings, Guido, de Die-Smulders, Christine, Smeets, Bert, de Wert, Guido

Journal:

European Journal of Human Genetics

Year:

2009

Language:

english

File:

PDF, 135 KB

english, 2009

13

Genetic Dilemmas and the Right to an Open Future

Annelien Bredenoord

Journal:

The American Journal of Human Genetics

Year:

2010

Language:

english

File:

PDF, 37 KB

english, 2010

14

Disclosure of individual genetic data to research participants: the debate reconsidered

Annelien L. Bredenoord, Hester Y. Kroes, Edwin Cuppen, Michael Parker, Johannes J.M. van Delden

Journal:

Trends in Genetics

Year:

2011

Language:

english

File:

PDF, 150 KB

english, 2011

15

Next-generation sequencing: does the next generation still have a right to an open future?

Bredenoord, Annelien L., de Vries, Martine C., van Delden, Johannes J. M.

Journal:

Nature Reviews Genetics

Year:

2013

Language:

english

File:

PDF, 196 KB

english, 2013

16

Disclosure and management of research findings in stem cell research and banking: policy statement

Isasi, Rosario, Knoppers, Bartha M, Andrews, Peter W, Bredenoord, Annelien, Colman, Alan, Hin, Lee Eng, Hull, Sara, Kim, Ock-Joo, Lomax, Geoffrey, Morris, Clive, Sipp, Douglas, Stacey, Glyn, Wahlstrom

Journal:

Regenerative Medicine

Year:

2012

Language:

english

File:

PDF, 822 KB

english, 2012

17

Placebo in Autologous Cell-Based Interventions

Koudstaal, Stefan, Niemansburg, Sophie L., Dib, Nabil, Wallet, Justin, Doevendans, Pieter A., Bredenoord, Annelien L., Chamuleau, Steven A.J.

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 60 KB

english, 2014

18

Identifiability and Privacy in Pluripotent Stem Cell Research

Isasi, Rosario, Andrews, Peter W., Baltz, Jay M., Bredenoord, Annelien L., Burton, Paul, Chiu, Ing-Ming, Hull, Sara Chandros, Jung, Ji-Won, Kurtz, Andreas, Lomax, Geoffrey, Ludwig, Tenneille, McDonald

Journal:

Year:

2014

Language:

english

File:

PDF, 128 KB

english, 2014

19

Disclosing Individual Genetic Research Results to Deceased Participants’ Relatives by Means of a Qualified Disclosure Policy

Bredenoord, Annelien L., van Delden, Johannes JM

Journal:

American Journal of Bioethics

Year:

2012

Language:

english

File:

PDF, 83 KB

english, 2012

20

A Thick Opt-Out Is Often Sufficient

Giesbertz, Noor A. A., Bredenoord, Annelien L., van Delden, Johannes J. M.

Journal:

American Journal of Bioethics

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

21

Stem Cell Trials for Cardiovascular Medicine: Ethical Rationale

Niemansburg, Sophie L., Teraa, Martin, Hesam, Husna, van Delden, Johannes J.M., Verhaar, Marianne C., Bredenoord, Annelien L.

Journal:

Tissue Engineering Part A

Year:

2014

Language:

english

File:

PDF, 186 KB

english, 2014

22

Societal impacts of regenerative medicine: reflections on the views of orthopedic professionals

Niemansburg, Sophie L, Tempels, Tjidde H, Dhert, Wouter JA, van Delden, Johannes JM, Bredenoord, Annelien L

Journal:

Regenerative Medicine

Year:

2015

Language:

english

File:

PDF, 876 KB

english, 2015

23

Clarifying assent in pediatric research

Giesbertz, Noor A A, Bredenoord, Annelien L, van Delden, Johannes J M

Journal:

European Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 200 KB

english, 2014

24

Regenerative medicine interventions for orthopedic disorders: ethical issues in the translation into patients

Niemansburg, Sophie L, van Delden, Johannes JM, Dhert, Wouter JA, Bredenoord, Annelien L

Journal:

Regenerative Medicine

Year:

2013

Language:

english

File:

PDF, 931 KB

english, 2013

25

Return of whole-genome sequencing results in paediatric research: a statement of the P3G international paediatrics platform

Knoppers, Bartha Maria, Avard, Denise, Sénécal, Karine, Bredenoord, Annelien L, Hall, Alison, Hens, Kristien, Pinxten, Wim, Wallace, Susan, Parry, David, Wright Clayton, Ellen

Journal:

European Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 167 KB

english, 2014

26

The Right to an Open Future Concerning Genetic Information

Bredenoord, Annelien L., de Vries, Martine C., van Delden, Hans

Journal:

American Journal of Bioethics

Year:

2014

Language:

english

File:

PDF, 82 KB

english, 2014

27

Reconsidering the ethics of sham interventions in an era of emerging technologies

Niemansburg, Sophie L., van Delden, Johannes J.M., Dhert, Wouter J.A., Bredenoord, Annelien L.

Journal:

Year:

2015

Language:

english

File:

PDF, 371 KB

english, 2015

28

Postmortem disclosure of genetic information to family members: active or passive?

Boers, Sarah N., van Delden, Johannes J.M., Knoers, Nine V., Bredenoord, Annelien L.

Journal:

Trends in Molecular Medicine

Year:

2015

Language:

english

File:

PDF, 293 KB

english, 2015

29

Consent procedures in pediatric biobanks

Giesbertz, Noor AA, Bredenoord, Annelien L, van Delden, Johannes JM

Journal:

European Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 270 KB

english, 2014

30

The inherent ethical challenge of first-in-human pluripotent stem cell trials

Habets, Michelle GJL, van Delden, Johannes JM, Bredenoord, Annelien L

Journal:

Regenerative Medicine

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014

31

Inclusion of Residual Tissue in Biobanks: Opt-In or Opt-Out?

Giesbertz, Noor A. A., Bredenoord, Annelien L., van Delden, Johannes J. M., Caplan, Arthur

Journal:

Year:

2012

Language:

english

File:

PDF, 99 KB

english, 2012

32

Next Generation DNA Sequencing: Always Allow an Opt Out

Bredenoord, Annelien L., Bijlsma, Rhodé M., van Delden, Hans

Journal:

American Journal of Bioethics

Year:

2015

Language:

english

File:

PDF, 77 KB

english, 2015

33

Reply to Waligora

Giesbertz, Noor A A, Bredenoord, Annelien L, van Delden, Johannes J M

Journal:

European Journal of Human Genetics

Year:

2014

Language:

english

File:

PDF, 115 KB

english, 2014

34

Preferences for genetic testing for colorectal cancer within a population-based screening program: a discrete choice experiment

Veldwijk, Jorien, Lambooij, Mattijs S, Kallenberg, Frank G J, van Kranen, Henk J, Bredenoord, Annelien L, Dekker, Evelien, Smit, Henriëtte A, de Wit, G Ardine

Journal:

European Journal of Human Genetics

Year:

2015

Language:

english

File:

PDF, 327 KB

english, 2015

35

Participant selection for preventive Regenerative Medicine trials: ethical challenges of selecting individuals at risk: Figure 1

Niemansburg, Sophie L, Habets, Michelle G J L, Dhert, Wouter J A, van Delden, Johannes J M, Bredenoord, Annelien L

Journal:

Journal of Medical Ethics

Year:

2015

Language:

english

File:

PDF, 191 KB

english, 2015

36

The social value of clinical research

Habets, Michelle GJL, van Delden, Johannes JM, Bredenoord, Annelien L

Journal:

BMC Medical Ethics

Year:

2014

Language:

english

File:

PDF, 279 KB

english, 2014

37

Data sharing in stem cell translational science: policy statement by the International Stem Cell Forum Ethics Working Party

Bredenoord, Annelien L, Mostert, Menno, Isasi, Rosario, Knoppers, Bartha M

Journal:

Regenerative Medicine

Year:

2015

Language:

english

File:

PDF, 713 KB

english, 2015

38

Broad Consent Is Consent for Governance

Boers, Sarah N., van Delden, Johannes J. M., Bredenoord, Annelien L.

Journal:

American Journal of Bioethics

Year:

2015

Language:

english

File:

PDF, 297 KB

english, 2015

39

Studying the lay of the land: views and experiences of professionals in the translational pluripotent stem cell field

Habets, Michelle GJL, van Delden, Johannes JM, Bredenoord, Annelien L

Journal:

Regenerative Medicine

Year:

2016

Language:

english

File:

PDF, 822 KB

english, 2016

40

Unsolicited findings of next-generation sequencing for tumor analysis within a Dutch consortium: clinical daily practice reconsidered

Bijlsma, Rhodé M, Bredenoord, Annelien L, Gadellaa-Hooijdonk, Christa G, Lolkema, Martijn PJ, Sleijfer, Stefan, Voest, Emile E, Ausems, Margreet GEM, Steeghs, Neeltje

Journal:

European Journal of Human Genetics

Year:

2016

Language:

english

File:

PDF, 275 KB

english, 2016

41

Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines

Daley, George Q., Hyun, Insoo, Apperley, Jane F., Barker, Roger A., Benvenisty, Nissim, Bredenoord, Annelien L., Breuer, Christopher K., Caulfield, Timothy, Cedars, Marcelle I., Frey-Vasconcells, Joyc

Journal:

Stem Cell Reports

Year:

2016

Language:

english

File:

PDF, 546 KB

english, 2016

42

Consent in psychiatric biobanks for pharmacogenetic research

van der Baan, Frederieke H., Bernabe, Rose D. C., Bredenoord, Annelien L., Gregoor, Jochem G., Meynen, Gerben, Knol, Mirjam J., van Thiel, Ghislaine J. M. W.

Journal:

The International Journal of Neuropsychopharmacology

Year:

2013

Language:

english

File:

PDF, 71 KB

english, 2013

43

Whole-exome sequencing in pediatrics: parents’ considerations toward return of unsolicited findings for their child

Cornelis, Candice, Tibben, Aad, Dondorp, Wybo, van Haelst, Mieke, Bredenoord, Annelien L, Knoers, Nine, Düwell, Marcus, Bolt, Ineke, van Summeren, Marieke

Journal:

European Journal of Human Genetics

Year:

2016

Language:

english

File:

PDF, 155 KB

english, 2016

44

Big Data in medical research and EU data protection law: challenges to the consent or anonymise approach

Mostert, Menno, Bredenoord, Annelien L, Biesaart, Monique CIH, van Delden, Johannes JM

Journal:

European Journal of Human Genetics

Year:

2016

Language:

english

File:

PDF, 66 KB

english, 2016

45

Organoid biobanking: identifying the ethics

Boers, Sarah N, van Delden, Johannes JM, Clevers, Hans, Bredenoord, Annelien L

Journal:

Year:

2016

Language:

english

File:

PDF, 91 KB

english, 2016

46

The unique status of first-in-human studies: strengthening the social value requirement

Habets, Michelle G.J.L., Delden, Johannes J.M. van, Bredenoord, Annelien L.

Journal:

Drug Discovery Today

Year:

2016

Language:

english

File:

PDF, 179 KB

english, 2016

47

Ethical clinical translation of stem cell interventions for neurologic disease

Cote, David J., Bredenoord, Annelien L., Smith, Timothy R., Ammirati, Mario, Brennum, Jannick, Mendez, Ivar, Ammar, Ahmed S., Balak, Naci, Bolles, Gene, Esene, Ignatius Ngene, Mathiesen, Tiit, Broekma

Journal:

Year:

2017

Language:

english

File:

PDF, 190 KB

english, 2017

48

One Size Fits All?: Ethical Considerations for Examining Efficacy in First-in-Human Pluripotent Stem Cell Studies

Habets, Michelle GJL, van Delden, Johannes JM, Niemansburg, Sophie L, Atkins, Harold L, Bredenoord, Annelien L

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 333 KB

english, 2016

49

Moral Duties of Genomics Researchers: Why Personalized Medicine Requires a Collective Approach

Vos, Shoko, van Delden, Johannes J.M., van Diest, Paul J., Bredenoord, Annelien L.

Journal:

Trends in Genetics

Year:

2017

Language:

english

File:

PDF, 1.40 MB

english, 2017

50

Ancillary Care Obligations for Social Media Platforms

Bredenoord, Annelien L., Boeckhout, Martin

Journal:

American Journal of Bioethics

Year:

2017

Language:

english

File:

PDF, 325 KB

english, 2017